PACE Hospitals is one of the best hospitals for tuberculosis (TB) treatment in Hyderabad, Telangana, India, offering expert lungs care, advanced diagnostic tests, and personalized treatment plans to ensure effective recovery. With cutting-edge facilities, we offer accurate TB detection through Gene-Xpert, a CBNAAT (catridge based nucleic acid amplification test), sputum tests, and chest X-rays, along with DOTS therapy (Directly Observed Treatment, Short-course), Multidrug-resistant Tuberculosis (MDR-TB) or Rifampicin-resistant Tuberculosis (RR-TB) treatment, and specialized care for brain, spine, and kidneys TB cases.
Our multidisciplinary team of pulmonologists & infectious disease specialists ensure comprehensive management, from early diagnosis to post-treatment follow-up, reducing complications and relapse risks. In case of experiencing persistent cough, fever, night sweats, or weight loss, visit PACE Hospitals for the best tuberculosis treatment in Hyderabad, India for comprehensive tuberculosis (TB) treatment.
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Appointment Desk: 04048486868
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PACE Hospitals
HITEC City and Madeenaguda
Hyderabad, Telangana, India.
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Appointment Desk: 04048486868
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Regards,
PACE Hospitals
HITEC City and Madeenaguda
Hyderabad, Telangana, India.
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a curable and preventable disease. However, the disease is very challenging to diagnose and treat. The World Health Organization (WHO) recommends a rapid molecular diagnostic test as the initial diagnostic test in individuals presenting signs and symptoms of tuberculosis. These rapid diagnostic tests include Xpert MTB/RIF (Xpert Mycobacterium tuberculosis/rifampicin) Ultra and Truenat assays. They have high diagnostic accuracy and will help in the early detection of tuberculosis and drug-resistant tuberculosis.
Mantoux test or tuberculin skin test (TST), interferon-gamma release assay (IGRA), or newer
Tuberculosis antigen-based skin test (TBST) can be used to identify people with TB infection.
The Approach of Infectious Disease Specialists towards the patient
The pulmonary tuberculosis diagnosis depends on whether the patient is being tested for latent, active pulmonary, or extrapulmonary TB disease. Diagnosis is established by a combination of radiology, microbiology, molecular methods, biomarkers, and the immunologic response to provocative testing. The sensitivity of diagnostic tests varies depending on factors such as pretest probability, immunological status, patient’s age, test timing, adherence to test procedures, and the ability to explain test results in the context of the patient's risk factors. The general physician or pulmonologist may inquire about the presenting symptoms and gather the complete medical history of the patient, including family history, as an initial approach in diagnosing TB.
The pulmonologist may consider the following before diagnosing TB:
Initial evaluation
Based on the above information, the pulmonologists may recommend the following tests:
From initial exposure to active disease, TB can progress through various stages. The following are the different stages of tuberculosis:
The differential diagnosis of tuberculosis occurs as a result of manifestations over prolonged periods. The following are included in the differential diagnosis of pulmonary tuberculosis:
A pulmonologist may consider the following key points before treating tuberculosis:
The following are the treatment goals of tuberculosis:
Pulmonary tuberculosis (TB) treatment involves complex antibiotic regimens, which can be challenging to adhere to. In the mid-20th century, primary anti-TB antibiotics were developed, playing a crucial role in treatment. However, the recent approval of two new antibiotics marks a significant breakthrough in TB management.
Effective TB prevention and treatment require seamless coordination between public health officials, primary care providers, and specialists, highlighting the importance of interprofessional collaboration in achieving TB control and eradication.
Tuberculosis exists in two forms: latent TB infection (inactive TB) and active TB disease. Both conditions are managed with antibiotic therapy, ensuring successful treatment and reducing the risk of transmission.
By treating latent TB, the risk of developing a disease in populations at high risk can be reduced. As per the World Health Organization, the rationale of treating patients with latent TB is based on the probability that the condition will progress from inactive TB to active TB disease, on the underlying epidemiology and burden of TB, and the likelihood of a broader public health impact.
Two first line oral anti-tubercular drugs for three months is recommended by the Centers for Disease Control and Prevention as the preferred preventive regimen for treating TB infection. This regimen is often prescribed because of its short duration and decreased incidence of liver toxicity compared to the 6 and 9 month regimens. Depending on the treatment plan, the antibiotics are prescribed for 3, 4, 6 and 9 months.
Adults and adolescents who are living with HIV with unknown or a positive TST (tuberculin skin test or IGRA (interferon-gamma release assay) can follow the daily antitubercular preventive therapy for at least 36 months.
Active tubercular disease treatment can generally take four, six, or nine months depending on the treatment plan. This treatment regimen involves the management of tuberculosis with different combinations of drugs. A 6-month treatment regimen that includes three first line antitubercular drugs for 2 months, followed by two first line antitubercular drugs for a duration of 4 months, is the preferred treatment for patients with susceptible TB and who adhere to treatment. This treatment plan is also recommended for both HIV-infected and uninfected individuals. However, in patients with HIV infection, it is necessary to monitor the clinical and bacteriologic response. If there is any evidence of a slow or suboptimal response, therapy should be prolonged.
Drug-resistant tuberculosis poses a greater risk of treatment failure compared to drug-susceptible TB treatment, and it requires alternative and often prolonged treatment regimens. This treatment regimen can be extended from 18 to 21 months and includes a variety of first-line, second-line, new, and repurposed agents during therapy. The risks of drug toxicities and patient difficulties with adherence are very high when treatment regimens are prolonged. Medication adherence can be improved with patient counseling, patient education, and through financial incentives.
In patients with drug susceptible tuberculosis (TB) who can complete the drug regimen, the cure rate exceeds 95 percent. Factors such as disease extent, treatment delay, comorbidities, age, the need for ventilation, drug resistance, and adverse drug reactions influence the outcome of the therapy. In patients who are treated for drug resistant TB (tuberculosis), the novel regimes will likely improve the outcomes of the treatment.
2018 WHO global estimates of successful treatment outcomes are given as follows:
In LMICs (low- and middle-income countries), the tuberculosis associated mortality rate is more than 80 percent. Tuberculosis is the leading cause of death in patients with HIV in the year 2022, the World Health Organization estimated 11.3 lakh deaths among HIV-negative individuals and 167,000 deaths among patients who are HIV positive. Prognosis estimates of untreated tuberculosis (TB) is difficult to calculate. Regional differences in healthcare resources, with either failed or never started treatment, individuals with underlying comorbidities and drug-resistant strains are difficult to estimate.
TB Treatment Cost in Hyderabad, India, varies based on factors such as the choice between government and private healthcare facilities, the specific medical interventions required, the patient’s overall health condition, diagnostic tests, medications, outpatient or inpatient care, duration of treatment, health insurance & coverage options.
The Indian government provides free first-line TB medications under the Revised National Tuberculosis Control Programme (RNTCP) through Directly Observed Treatment, Short-course (DOTS) clinics. This program ensures that essential TB medications are available at no cost, making treatment accessible to all patients.
In private healthcare facilities, costs can vary depending on the services provided such as Consultation Fees (₹400 to ₹800), Diagnostic Tests ₹550 to ₹7,800 (MTB Culture & Identification, MTB Drug Sensitivity, BACTEC Culture Sensitivity), Hospitalization Charges - ₹25,000 to ₹80,000, Intensive Care Unit (ICU) Charges - ₹5,000 to ₹7,000 per day etc.
Treatment costs may vary depending on individual medical needs, the presence of drug-resistant TB strains, and the requirement for specialized procedures. Patients should consult with pulmonologists or hospital for a precise cost estimate based on their specific condition.
Tuberculosis is caused by the bacterium Mycobacterium tuberculosis. When an individual breathes in TB germs, the germs adapt in the lungs and start growing. As they grow, they move to various other parts of the body, such as the kidney, spine, and brain, via blood.
Symptoms of tuberculosis depends on where in the body the bacteria is growing and multiplying. TB usually affects the lungs, so the common signs and symptoms of pulmonary tuberculosis are cough, cough with sputum, chest pain, fever, chills, weight loss, fatigue, and loss of appetite.
Signs and symptoms of tuberculosis in other parts of the body include:
Yes, tuberculosis can be cured. It can be treated with antibiotics; tuberculosis treatment requires a course of antibiotics for about 6 to 9 months. Medication adherence is important to prevent relapse of the disease and to prevent the development of multiple drug-resistant TB.
The following measures need to be taken to prevent tuberculosis infection and spread:
If TB is not treated early, it can lead to permanent lung damage. Untreated TB can cause infection of the bones, spine, brain, spinal cord, and other parts of the body. In the long term, it can lead to death. TB remains the most prevalent infectious disease and leading cause of death worldwide.
Tuberculosis is an infectious disease caused by the bacterium “Mycobacterium tuberculosis,” which commonly affects the lungs. It spreads via air when a TB infected individual coughs or sneezes in the open air.
In latent TB infection, bacteria is present in the body, but it is inactive. Signs and symptoms do not show, a tuberculin skin test is positive, and the X-ray shows no abnormal findings. In active TB disease, the bacteria is present, and it is active and starts multiplying in the body. Signs and symptoms appear in this stage with positive tuberculin test. X ray shows abnormal findings.
Individuals who are at risk for developing tuberculosis include:
DOT, or directly observed therapy, is the most effective strategy to ensure medication adherence in patients with tuberculosis. A health care worker or any other designated person watches the TB patient taking each dose of prescribed medication on time. It can be assigned in person or remotely (on phone or computer), DOT when conducted remotely is called electronic DOT (eDOT).
Multi drug resistant (MDR) tuberculosis is a type of tuberculosis that is caused by a bacterium that is resistant to at least two types of antibiotics, which are considered as first line drugs in treating tuberculosis.
The complications of tuberculosis arise from the involvement of the infected organs and the potential toxicities of the drugs used for treatment. The potential complications caused by tuberculosis are septic shock, airway obstruction, pneumonia, hemoptysis (coughing of blood from lungs), meningitis (inflammation of tissue surrounding brain and spinal cord), peritonitis (inflammation of lining of abdomen), renal abscess, and infertility. Complications associated with anti-TB therapy include hepatitis (inflammation of the liver), optic neuritis (inflammation of the optic nerve).
Metro Pillar Number C1772, Beside Avasa Hotel, Hitech City Road, Near HITEC City Metro Station, Hyderabad, Telangana, India.
Mythri Nagar, Beside South India Shopping Mall, Hafeezpet, Madeenaguda, Hyderabad, Telangana, India.
040 4848 6868
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