Gallbladder cancer: need urgent attention

Pace Hospitals

Globally about 1,78,101 gallbladder cases are estimated to occur in the year 2015.

What causes gallbladder cancer?

Gallbladder cancer is an aggressive GI cancer with early liver and bile duct involvement causing jaundice and rapid spread to other organs. A very common cancer in the cow belt UP, Bihar and Bengal (endemic area with one of the world’s highest incidence) it is now reported with increasing frequency in other parts of country.

What are the risk factors for gallbladder cancer?

A risk factor is anything that affects your chance of getting a disease .But having a risk factor, or even several risk factors, does not mean that a person will get the disease. And many people who get the disease may have few or no known risk factors.

There are several risk factors that make a person more likely to develop gallbladder cancer. Many of these are related in some way to chronic inflammation (irritation and swelling) in the gallbladder.

  • Gallstones: Gallstones are the most common association for gallbladder cancer. At least 3 out of 4 people with gallbladder cancer have gallstones when they are diagnosed. But wether they cause gallbladder cancer is debatable.gallstones are very common, and gallbladder cancer is quite rare, Most people with gallstones never develop gallbladder cancer. PREVENTION OF CANCER IS NEVER AN INDICATION FOR GALLBLADDER SURGERY EVEN WITH STONES
  • Porcelain gallbladder: Porcelain gallbladder is a condition in which the wall of the gallbladder becomes covered with calcium deposits. It sometimes occurs after long-term inflammation of the gallbladder (cholecystitis), which can be caused by gallstones. People with this condition have a higher risk of developing Gallbladder cancer
  • Female gender: Gallbladder cancer occurs more than twice as often in women. Gallstones and gallbladder inflammation are important risk factors for gallbladder cancer and are also much more common in women than men.
  • Obesity: Patients with gallbladder cancer are more often overweight or obese than people without this disease.
  • Older age: Gallbladder cancer is seen mainly in older people, but younger people can develop it as well.
  • Choledochal cysts: Choledochal cysts are bile-filled sacs that are connected to the common bile duct, the tube that carries bile from the liver and gallbladder to the small intestine.The cysts can grow large over time and may contain as big as 10 cm ( normal bile duct is 6-7 mm) The cells lining the sac often have areas of pre-cancerous changes, which increase a person’s risk for gallbladder cancer.
  • Abnormalilities in bike duct: such a abnormal pancreatobiliary union increase reflux of pancreatic juice into bileducts causing gallbladder cancer. This can be detected only on imaging
  • Gallbladder polyps: A gallbladder polyp is a growth that bulges from the surface of the inner gallbladder wall. Some polyps are formed by cholesterol deposits in the gallbladder wall. Others may be small tumors (either cancerous or benign) or may be caused by inflammation. Polyps larger than 1 centimeter (almost a half inch) are more likely to be cancer, so doctors often recommend removing the gallbladder in patients with gallbladder polyps that size or larger.
  • Primary sclerosing cholangitis: In primary sclerosing cholangitis (PSC), there is inflammation and scarring of the bile ducts. People with this disease have an increased risk of cancer of the gallbladder and bile ducts. Many people with PSC also have ulcerative colitis, a type of inflammatory bowel disease.
  • Industrial and environmental chemicals: Some studies in lab animals have suggested that chemical compounds called nitrosamines may increase the risk of gallbladder cancer. Other studies have found that gallbladder cancer might occur more in workers in the rubber and textile industries than in the general public. More research is needed in this area to confirm or refute these possible links.
  • Typhoid: People chronically infected with salmonella (the bacterium that causes typhoid) and those who are carriers of the disease are more likely to get gallbladder cancer than those not infected. This is probably because the infection can cause gallbladder inflammation.
  • Family history: Most gallbladder cancers are not found in people with a family history of the disease. A history of gallbladder cancer in the family seems to increase a person’s chances of developing this cancer, but the risk is still low because this is a rare disease.
Original Post: https://goo.gl/95uJGp

Share on

Request an appointment

Fill in the appointment form or call us instantly to book a confirmed appointment with our super specialist at 04048486868

Appointment request - health articles

Successful Renal Artery Coil Embolization done for CAD & Renal Vascular Issues at PACE Hospitals
By PACE Hospitals July 10, 2025
A case study from PACE Hospitals Hyderabad showing the successful use of Renal Artery Coil Embolization to treat CAD and renal vascular issues by relieving pain and minimizing complications.
World Population Day 2025 theme, history, and importance illustrated with diverse people
By PACE Hospitals July 10, 2025
Explore World Population Day 2025 — theme, history & importance of the day observed every 11 July to highlight global population issues & sustainable development goals.
Membranous Nephropathy Symptoms, Causes, Diagnosis & Treatment Explained by Dr. A Kishore Kumar from
By PACE Hospitals July 9, 2025
In this video Dr. A Kishore Kumar from PACE Hospitals shares expert insights on Membranous Nephropathy including causes, symptoms, diagnosis methods and effective treatment strategies.
Successful ESD procedure done for gastric polyp removal at PACE Hospitals, Hyderabad
By PACE Hospitals July 9, 2025
Learn about successful Gastric Polyp removal in a 42-year-old at PACE Hospitals using Endoscopic Submucosal Dissection, a safe and effective minimally invasive procedure.
Uterine fibroid specialists | Best doctor for uterine fibroids in Hyderabad
By PACE Hospitals July 8, 2025
PACE Hospitals brings you the best uterine fibroid specialists in Hyderabad, offering advanced gynecological treatments focused on your reproductive health and wellness.
Gastroenteritis Symptoms, Causes & Treatment Explained in Telugu by Dr. M Sudhir from PACE Hospitals
By PACE Hospitals July 8, 2025
గ్యాస్ట్రోఎంటరైటిస్పై పూర్తి అవగాహన! కారణాలు, లక్షణాలు, పరీక్షలు, చికిత్సలు, జాగ్రత్తల గురించి PACE Hospitals డా. ఎమ్ సుధీర్ గారి సలహాలు మరియు సూచనలు ఈ వీడియోలో తెలుసుకోండి.
Successful ACL Reconstruction performed to restore mobility at PACE Hospitals.
By PACE Hospitals July 8, 2025
Discover how a 27-year-old regained full mobility after knee trauma through ACL Reconstruction at PACE Hospitals, restoring strength, motion, and returning to daily life.
epilepsy specialist in Hyderabad | best epilepsy doctor in Hyderabad | best doctor for epilepsy
By PACE Hospitals July 7, 2025
Meet the best doctor for epilepsy in Hyderabad for expert care. Our epilepsy specialist & Neurologists provides cutting-edge treatment to help patients manage seizures effectively. Schedule your consultation today!
Breast Lump Symptoms, Causes & Treatment Explained in Telugu by Dr. K Meena from PACE Hospitals
By PACE Hospitals July 7, 2025
రొమ్ములో గడ్డల లక్షణాలు, కారణాలు, దశలు, పరీక్షలు మరియు చికిత్సలు తెలుసుకోవడానికి PACE Hospitals ఆంకాలజిస్ట్ డాక్టర్ కె మీనా గారి అవగాహన వీడియోను తప్పక చూడండి.
Show More